Lina Chen, Professor of Pharmaceutical Analysis


Professor Lina Chen

Full Name:    Lina Chen

Academic Position:    Professor of pharmaceutical analysis;

              Expert in network evaluation of national natural science foundation of China


Awards: 

1.  Second prize of jiangsu science and technology award of Traditional Chinese Medicine (ranked second).

2. Training candidates for outstanding young backbone teachers of Blue and Blue Project in Colleges and universities of Jiangsu Province.

3. Excellent young and middle-aged academic leaders of Nanjing Medical University.

University                                4. Advanced individuals in scientific and technological work during the Twelfth-Five year plan.

                                                 

                                                  Hosting projects:

1. Three projects of the National Natural Science Foundation, China

2. One project of Post-doctoral Science Foundation, China

3. Two projects of the Natural Science Foundations of Jiangsu Education Department, china

4. One project of the Research and Development Fund Project for Intelligent Health Science and Technology Innovation of Nanjing Medical University-Su Yan

5. Five school-level projects of Nanjing Medical University

6. Presided or Join in the compilation of six schoolbooks for the 12th and 13th five-year plan

7. As a major participant, completed in one of the 863 projects of the National Natural Science Foundation and three projects of the National Natural Science Foundation.


Research interests:

Research interests are focused on the application of modern analytical techniques in the study of active ingredients of natural medicines and the study of active ingredients of natural medicines and their quality evaluation.

Publications:

1. Jiaojiao Huang, Chenghong Sun, Dandan Yao, Chong-Zhi Wang, Lei Zhang, Yu Zhang, Lina Chen , Chun-Su Yuan .Novel surface imprinted magnetic mesoporous silica as artificial antibodies for efficient discovery and capture of candidate nNOS–PSD -95 uncouplers for stroke treatment, Journal of Materials Chemistry B , 2018, 6, 1531-1542.

2. Dandan Yao , Lei Zhang , Jiaojiao Huang , Chenghong Sun , Yu Zhang , Xiaoli Gu , Chong-Zhi Wang , Fei Li , Lina Chen , Chun-Su Yuan. A surface magnetic imprinted polymers as artificial receptors for selective and efficient capturing Of new neuronal nitric oxidesynthase–post synaptic density protein-95 uncouplers, Journal of Pharmaceutical and Biomedical Analysis , 2018, 154: 180–190.

3. Xiaoli Gu, Jiaojiao Huang, Lei Zhang, Yu zhang, Chong-Zhi Wang, Chenghong Sun, Dandan Yao, Fei Li, Lina Chen , Chun-Su Yuan. Efficient discovery and capture of new neuronal nitric oxide synthase-postsynaptic density Protein-95 uncouplers from herbal medicines using magnetic molecularly imprinted polymers as artificial antibodies. Journal of Separation Science, 2017,40(17):3522-3534.

4. Chenghong Sun, Jinhua Wang, Jiaojiao Huang, Dandan Yao, Chong-Zhi Wang, Lei Zhang, Shuying Hou,Lina Chen ,Chun-Su Yuan. The multi-template molecularly imprinted polymer based on SBA-15 for selective separation And determination of Panax notoginseng Saponins simultaneously in biological samples. Polymers, 2017, 9(12): 653.

5. Hongliang He, Xiaoli Gu, Liying Shi, Junli Hong, Hongjuan Zhang, Yankun Gao, Shuhu Du, Lina Chen . Molecularly imprinted polymers based on SBA-15 for selective solid-phase extraction of baicalein from plasma samples. Analytical and Bioanalytical Chemistry, 2015, 407(2): 509–519.

6. Hongliang He, Hong Li, Yankun Gao, Dong Chen, Li Ying Shi, Jin Peng, Shuhu Du, Lina Chen . A novel molecularly imprinted polymer for the solid-phase extraction of Tanshinones from serum, Analytical Letters, 2015, 48: 47-60.

7. Shuying Hou, Songling Yang, Hongliang He, Yan Chen, Jinhua Wang, Yang Wang, Lina Chen . Multi-templates molecularly imprinted polymer for the specific solid-phase extraction of saponins from Panax notoginseng herbal extract. Current Pharmaceutical Analysis, 2015, 11(3): 292-299.

8. Xiaoli Gu, Hongliang He, Chong-zhi Wang, Yankun Gao, Hongjuan Zhang, Junli Hong, Shuhu Du, Lina Chen , Chun-su Yuan. Synthesis of surface nanomolecularly imprinted polymers for sensitive baicalin detection from biological samples. RSC Advances , 2015, 5, 41377–41384.

9. Hong Li, Hongliang He, Jiaojiao Huang, Chong-Zhi Wang, Xiaoli Gu, Yankun Gao, Hongjuan Zhang, Shuhu Du, Lina Chen , Chun-Su Yuan. A novel molecularly imprinted method with computational simulation for the affinity isolation and Knockout of baicalein from Scutellaria baicalensis. Biomedical Chromatography, 2016,30(2):117-125.

10. Xianjun Jia, Hong Li, Jing Luo, Qing Lu, Yan Peng, Shuhu Du, Guijun Zhang, Lina Chen . Rational design of core-shell molecularly imprinted polymer based on computational simulation and Doehlert experimental optimization: application to the separation of Tanshinone IIA from Salvia Miltiorrhiza Bunge. Analytical and Bioanalytical Chemistry, 2012, 403(9): 2691–2703.

Representational invention patent:

1. Preparation of core-shell composite nano-surface molecularly imprinted polymers using tanshinones as templates Patent No: ZL2010167614.0 Authorization Date: 2011.09.21Applicant: Lina Chen, Shuhu du, Xianjun jia, Liping Liu.

1. Preparation and application of molecularly imprinted polymers using baicalein as template Patent No: ZL201310408025.0Authorization Date: 2016.04.27Applicants: Lina Chen, Hong Li, Hongliang He, Yankun Gao, Liying Shi, Shuhu du

2. Preparation of molecularly imprinted polymers templated by several and monodispersed active saponins of panax notoginseng Patent No: ZL201310495697.X Authorization Date: 2016.01.06Applicant: Lina Chen, Hongliang He, Yankun Gao

3.  Preparation of surface imprinted polymer based on SBA-15   Patent No: ZL201310496400.1Authorization Date: 2016.01.20Applicant: Lina Chen, Hongliang He, Liying Shi, Qingqing Cheng, Yankun Gao, Shuhu du.




Twelfth Five-Year Plan.