Ji Fu Wei,Director of Research Division of Clinical pharmacology


Personal Information

Professor and Director of Research Division of Clinical Pharmacology, the First Affiliated Hospital ofNanjingMedical University

Office Address:  300 Guangzhou Road, Nanjing 210029, Jiangsu Province, China

Office Tel: ( 86 ) 025 - 68306984

E-mail:  weijifu@hotmail.com

  

Education

Institution Time Degree

Anhui University, China 19 93 -19 97 BS

Kunming Institute of Zoology, CAS19 98 - 2003 Ph.D.

Postdoctoral Training

2003  - 2005 Postdoctoral Fellow  ,  Shantou  University, China

Research Interests

Identification of new allergens, early warning mechanisms for drug allergies, and the development of desensitization vaccines.


Grants

1.  National Natural Science Foundation of China (No. 81871265), 2019/01-2022/12

2.  Joint Funds of the National Natural Science Foundation of China (No. U1832212), 2019/01-2022/12

3.  National Key R&D Program of China (No. 2017YFC0910001), 2017/07-2022/12

4.  Innovation team of Science and education Project in Jiangsu Province (CXTDA2017049), 2017/01-2021/12

5.  “333 high level talents project” in Jiangsu province (No. BRA2017546), 2017/08-2019/08

6.  National Natural Science Foundation of China (No. 81571568), 2016/01-2019/12

7.  National Natural Science Foundation of China (No. 31340073), 2014/01-2014/12

8.  National Natural Science Foundation of China (No. 81273274), 2013/01-2014/12

9.  National Natural Science Foundation of China (No. 30972822), 2010/01-2012/12

10.  National Natural Science Foundation of China (No. 30801016), 2009/01-2011/12


Selected Publications as corresponding or first authors

  

2019

1.  Tang, R, Wang ZX, Ji CM, Leng PSC, Woo E, Chang C, Wang M, Liu B, Wei JF , Sun JL. Regional Differences I     n- Food Allergies. Clin Rev Allergy Immunol. 2019 Jan 5

2 .  Zhu L, Li X, Shi L, Wu J, Qian JY, Xia TS, Zhou WB, Sun X, Zhou XJ, Wei JF  , Ding Q. Rapamycin enhances the sensitivity of ER-positive breast cancer cells to tamoxifen by upregulating p73 expression Oncol Rep. 2019 Jan;41(1):455-464

3. Si S, Z Wang, Yang H, the Z Han, Tao J, Chen H, K Wang, Guo M, R & lt Tan, Wei JF  , Gu M. Impact of nucleotide single p     olymorphisms on P450 oxidoreductase and peroxisome proliferator -activated Receptor alpha On tacrolimus pharmacokinetics in renal transplant recipients. Pharmacogenomics J. 2018 Oct 15


2018

1.    Li X, Wang W is IS, the Y The Fan, The the Y Wei, Yu LQ, JF Wei, Wang YF. Anticancer Efficiency of cycloartane Triterpenoid Derivatives Isolated from C  imicifuga yunnanensis Hsiao the ON Triple-negative cells Res Manag 2018 On Dec. 6 ;10: 6715-6729

2 . The Sun X-, the Y Hu, Wu J, Shi L, Zhu L, the PW The Xi, JF Wei, Q. Ding RBMS2 inhibits     Proliferation by Stabilizing    of P21 in the mRNA Breast Cancer J Exp Clin Cancer Res. 4 On Dec 2018;.. 37 [( 1): 298.

3. Guo M, Wang ZJ, Yang HW, Meng L, Tan RY, Gu M, Wei JF. Influence of Genetic Polymorphisms on Mycophenolic Acid Pharmacokinetics a nd Patient Outcomes in Renal Transplantation. Curr Drug Metab. 2018;19(14): 199-1205.

4. Cao M, Ji C, Zhou Y, Huang W, Ni W, Tong X, Wei JF  . Sphingosine kinase  inhibitors: A patent review. Int J Mol Med. 2018 May;41(5):2450-2460.

5. Tang J, Wang F, Cheng G, Si S, Sun X, Han J, Yu H, Zhang W, Lv Q, Wei JF  , Yang    H. Wilms' tumor 1-associating protein promotes renal cell carcinoma proliferation b y regulating CDK2 mRNA stability. J Exp Clin Cancer Res. 2018 Feb 27;37(1):40.

6. Wang Z, Yang H, Si S, Han Z, Tao J, Chen H, Ge Y, Guo M, Wang K, Tan R, WeiJF  , Gu M. Polymorphisms of nucleotide factor of activated T cells cytoplasmic 2 and 4 and the risk of acute rejection following kidney transplantation. World J Urol. 2018 Jan;36(1):111-116.

7. Wang DW, Ni WW, Zhou YJ, Huang W, Cao MD, Meng L, Wei JF  . Expression, purification and epitope analysis of Pla a 2 allergen from Platanus acerifolia pollen. Mol Med Rep. 2018 Jan;17(1) :394-399.

8. Zhou Y, Ji C, Cao M, Guo M, Huang W, Ni W, Meng L, Yang H, Wei JF  . Inhibitors    targeting the SUMOylation pathway: A  patient review 2012-2015 Patent A MoI.Med 2018 Jan; 41 is (. 1):. 3-12.

9. Li H, Shi FH, Huang SY, Zhang SG, Gu ZC, Wei JF. Clinical adverse effects of natalizumab: Protocol for a meta-analysis of randomized double-blind placebo-controlled clinical trials. Medicine (Baltimore). 2018 Jul ;97(28):e11507.


2017

1. Zhou XJ, Wu J, Shi L, Li XX, Zhu L, Sun X, Qian JY, Wang Y, Wei JF , Ding Q.  PTEN expression is upregulated by a RNA-binding protein RBM38 via enhancing its  mRNA stability in breast Cancer. Journal of Experimental & Clinical Cancer Research, 2017, 36(1): 149.

2. Wu J, Zhou XJ, Sun X, Xia TS, Li XX, Shi L, Zhu L, Zhou WB, Wei JF , Ding Q.    RBM38 is involved in TGF-β-induced epithelial-to-mesenchymal transition by stabilizing zonula Occludens-1 mRNA in breast cancer. Br J Cancer. 2017 Aug 22;117(5):675-684.

3. Wang Z, Yang H, Guo M, the Z of The The Han, Tao J, Chen H, Ge Y, Wang K, Tan R,   Wei JF   , Gu     M. The Impact of Component complement. On single nucleotide polymorphisms renal Transplant Recipients with antibody-mediated rejection. Oncotarget. 2017 Oct 10;8(55):94539-94553.

4.     Ni WW , Wang an LB, Zhou YJ, Cao the MD, Huang W is, Guo M, Ji the CM, the Sun JL, Wei JF . The Expression, Purification and Epitope Analysis of Pla A. 3 allergen From Platanus acerifolia Pollen. MoI Med the Rep. 2017 Sep; 16(3): 2851-2855.

5.     Cao M, Sun X, Zhou Y, Huang W, Meng L, Wei JF . Poly (ADP-Ribosyl) Polymerase  I Inhibitors: A Patent Review. Recent Pat Anticancer Drug Discov. 2017;12(3):208-220 .

6.     Ni WW, Huang W, Wu DQ, Zhou YJ, Ji CM, Cao MD, Guo M, Sun JL, Wei JF  .  Expression and purification of a major allergen, Pla a 1, from Platanusacerifolia pollen and the preparation of its Mol Med Rep.2017 Sep;16(3):2887-2892.

7. Ni WW, Cao MD, Huang W, Meng L, Wei JF  . Tryptase inhibitors: a patent review.  Expert Opin Ther Pat. 2017 May 3:1-10.

8. Li XX , Shi L , Zhou XJ  , Wu J  , Xia TS , Zhou WB , Sun X , Zhu L , Wei JF  , Ding Q  . The role of c-Myc-RBM38 loop in the growth suppression in breast cancer .     J Exp Clin Cancer Res 2017 J Exp Clin Cancer Res. 11 On Apr; 36 (. 1): 49

9. Lou P, Li C, Shi L, Xia TS, Zhou W, Wu J, Zhou X, Li X, Wang Y, Wei JF , Ding  Q. RNPC1 enhances progesterone receptor functions by regulating its mRNA stability in breast cancer. Oncotarget 2017 Mar 7; 8(10): 16387-16400.

10. Yang H, Yang L, Wang DW, Wei JF  , He S. Anaphylactic shock caused by  haemocoagulase injection in China. Exp Ther Med. 2017 Apr;13(4):1547-1553.

11. Hu Y, Yang L, Yang H, He S, Wei JF . Identification of snake venom allergens by  two-dimensional electrophoresis followed by immunoblotting. Toxicon. 2017 Jan;125:13-18.

12. Li X, Tang J, Huang W, Wang F, Li P, Qin C, Qin Z, Zou Q, Wei J , Hua L, Yang  H, Wang Z. The M6A methyltransferase METTL3: acting as a tumor suppressor in renal Cell carcinoma. Oncotarget. 2017 Oct 10;8(56):96103-96116.

13. Wang YJ, Li L, Song WJ, Zhou YJ, Cao MD, Zuo XR, Wei JF  . Canis familiaris  allergen Can f 6: expression, purification and analysis of B-cell epitopes in Chinese dog allergic children. Oncotarget. 2017 Oct 13; 8 (53): 90796-90807.


2016

1. Yang ZC, Yu F, Wang YQ, Wei JF. Stereoselective Pharmacodynamics and Pharmacokinetics of Proton Pump Inhibitors. Curr Drug Metab. 2016;17(7):692-702.

2. Jin M, Yang HW, Tao AL, Wei JF  . Evolution of the protease-activated receptor family in vertebrates. International Journal of Molecular Medicine, 2016, 37(3): 593-602.

3. Fu YY, Chen Q, the CM Ji, Wei JF Rsal of CYP2E1 polymorphism and susceptibility of Gastrointestinal cancers: A Meta-Analysis of Case-Control 35 s Int J Clin Exp Med, 2016;. 9 (2): 2666-2676 .

4. Cheng G, Ji C, Yang N, Meng L, Wei JF . RNA-binding protein RBM38: acting as a tumor suppressor in colorectal cancer. Int J Clin Exp Med 2016;9(4):7115-7126 .

5. Tong X, Guo M, Jin M, Chen H, Li Y, Wei JF  . In silico epitope prediction,    expression and functional analysis of Per a 10 allergen from the American cockroach. Int J Mol Med. 2016 Dec;38(6 ): 1806-1814.

6. Yang H, Chen H, Jin M, Xie H, He S, Wei JF  . Molecular cloning, expression, IgE    binding activities and in silico epitope prediction of Per a 9 allergens of the American cockroach. Int J Mol Med. 2016 Dec ;38(6): 1795-1805.

7. Zhao ZT, Ji CM, Yu WJ, Meng L, Hawro T, Wei JF , Maurer M. Omalizumab for the    treatment of chronic spontaneous urticaria: A meta-analysis of randomized clinical trials. J Allergy Clin Immunol. 2016 Jun;137 (6): 1742-1750.


2015

1. Shi L, Xia TS, Wei XL, Zhou W, Xue J, Cheng L, Lou P, Li C, Wang Y, Wei JF , Ding Q . Estrogen receptor (ER) was regulated by RNPC1 stabilizing mRNA in ER Cancer. Oncotarget, 2015, 6(14): 12264-12278.

2. Cheng Y,  Y Xiao, Deng X, Wei JF .  Metabolomics in bladder Cancer:. International's A Systematic Review & apos apos, Journal of Clinical Experimental Medicine.8, 2015. (7. The.): 11052-11063.

3. Wei JF , Xu TR, Yu MC, Zhou XD, Zhao ZT, Jin Y. Protein Drugs Related to Allergic Reaction. Biomed Res Int. 2015; 2015:614048.

4. Yuan HY, Zhang XL, Zhang XH, Meng L, Wei JF    . Analysis of patents on     anti-rheumatoid arthritis therapies issued in China. Expert Opin Ther Pat. 2015;25(8):909-30.

5. Jiang AP, Jiang JF, Wei JF    , Guo MG, Qin Y, Guo QQ, Ma L, Liu BC, Wang X,     Veazey RS, Ding YB, Wang JH. Human Mucosal Mast Cells Capture HIV-1 and Mediate Viral Trans -Infection of CD4+ T Cells. J Virol. 2015 Dec 30;90(6):2928-37.