Chen Jin
1. Personal Information
Title/Position: Professor
Correspondence Address: School of Public Health, Nanjing Medical University, 101 Longmian Av., Jiangning District, Nanjing, Jiangsu Province, 211166, P.R. China.
Telephone: 86-25-86868248
E-mail: jchen@njmu.edu.cn
2. Education
INSTITUTION | DEGREE | MM/YY | FIELD OF STUDY |
Nanjing University | B.S. | 06/01 | Chemistry |
Nanjing University | Ph.D. | 09/06 | Bioanalytical Chemistry |
3. Research Interests
Our lab has been mainly focused on the following topics:
1. Developing biosensing platforms including cytosensors for the sensitive determination of tumor markers and for the evaluation of cytotoxicity.
2. Protein-based functional materials used for modern bioanalysis.
4. Selected Publications
Peer-reviewed articles as corresponding author:
1. Xu, Z. et al. A general method to regenerate arrayed gold microelectrodes for label-free cell assay. Anal. Biochem. 516, 57-60 (2017).
2. Wang, H. Q. et al. Three-Dimensionally controllable synthesis of multichannel silica nanotubes and their application as dual drug carriers. ChemPlusChem 80, 1615-1623 (2015).
3. Chen, J. et al. Self-assembly of the chaperonin GroEL nanocage induced at submicellar detergent. Sci. Rep. 4 (2014).
4. Zhang, Q.#, Chen, J.# Nucleotide-induced conformational changes of tetradecameric GroEL mapped by H/D exchange monitored by FT-ICR mass spectrometry. Sci. Rep. 3, 1247 (2013). #co-first
5. Chen, J. et al. Fibrillogenic propensity of the GroEL apical domain: A Janus-faced minichaperone. Febs Lett. 586, 1120-1127 (2012).
5. Scholarly and Professional Activities
Oral talk
Nucleotide-induced GroEL conformational changes, The 3rd Korea-Japan seminar on biomolecular sciences, Jeju, Korea, 2011
Alpha-crystallin domain assembly and GroEL dynamics, Workshop on recent advances in protein folding and molecular chaperones, Beijing, China, 2010.
Dissect a bimolecular mechanism of ATP binding to the chaperonin GroEL, OzBio2010 conference, Melbourne, Australia, 2010.
Honors
Specially-appointed professor of Jiangsu Province, 2015
Young eastern scholar, Shanghai, 2015
Young Investigator Travel Grant, The Protein Society, USA, 2012
International YSF fellowship, IUBMB, Australia, 2010
Alexander von Humboldt Fellowship, Germany, 2006-2008
