王建明

Wang Jianming

  

1. Personal Information

Title/Position: Professor/ Deputy dean

Correspondence Address: Department of Epidemiology, School of Public Health, Nanjing Medical University,101 Longmian Ave., Jiangning District, Nanjing , 211166 China.

Telephone: 86-25-86868438

E-mail: jmwang@njmu.edu.cn

  

2. Education

INSTITUTION

DEGREE

MM/YY

FIELD OF STUDY

Nanjing Medical University

BSc.

07/89

Preventive Medicine

Fudan University

MSc.

06/04

Epidemiology and Biostatistics

Fudan University

Ph.D.

07/07

Epidemiology and Biostatistics

Charite Medical School,Humboldt and Free University, Berlin,Germany

MSc.

09/07

International Health

UT MD Anderson Cancer Center, Texas, USA

Visiting scientist

04/10

Epidemiology

UC Davis, CA, USA

Visiting scientist

01/12

Epidemiology

 

3. Research Interests

(1) Infectious disease epidemiology

Tuberculosis epidemiology

(2) Cancer epidemiology

Epigenetics of esophageal cancer and breast cancer

(3) Health service research

  

4. Selected Publications

1. Wu L, Shen Y, Peng X, Zhang S, Wang M, Xu G, Zheng X, Wang J*, Lu C*. Aberrant promoter methylation of cancer-related genes in human breast cancer. Oncol Lett 2016; 12: 5145-5155

2. Lu W, Feng Y, Wang J*, Zhu L*. Evaluation of MTBDRplus and MTBDRsl in Detecting Drug-Resistant Tuberculosis in a Chinese Population. Disease Markers. 2016,2016:2064765

3. Zhang Q, Wang M, Li X, Wang H*, Wang J*. Do symptom-based questions help screen COPD among Chinese populations? Sci Rep. 2016,6:30419.

4. Wang M, Xu G, Lü L, Xu K, Chen Y, Pan H, Burstrom B, Burstrom K, Wang J*. Genetic polymorphisms of IL-17A, IL-17F, TLR4 and miR-146a in association with the risk of pulmonary tuberculosis. Sci Rep. 2016,6:28586.

5. Shen Y, Peng X, Wang M, Zheng X, Xu G, Lü L, Xu K, Burstrom B, Burstrom K, Wang J*. Family member-based supervision of patients with hypertension: a cluster randomized trial in rural China. J Hum Hypertens. 2016 Feb 25. doi: 10.1038/jhh.2016.8. [Epub ahead of print]

6. Yue J, Mao X, Xu K, Lü L, Liu S, Chen F, Wang J*. Prevalence, Awareness, Treatment and Control of Diabetes Mellitus in a Chinese Population. PLoS One. 2016,11(4):e0153791.

7. Zhang S, Pan H, Peng X, Lu H, Fan H, Zheng X, Xu G, Wang M, Wang J*. Preventive use of a hepatoprotectant against anti-tuberculosis drug-induced liver injury: A randomized controlled trial. J Gastroenterol Hepatol. 2016,31(2)409-416.

8. Zheng X, Mao X, Xu K, Lü L, Peng X, Wang M, Xu G, Hua Z, Wang J, Xue H, Wang J*, Lu C*. Massive Endoscopic Screening for Esophageal and Gastric Cancers in a High-Risk Area of China. PLoS One. 2015,10(12): e0145097.

9. Qiu S, Shen Y, Pan H, Wang J*, Zhang Q*. Effectiveness and safety of oseltamivir for treating influenza: An updated meta-analysis of clinical trials. Infectious diseases (formerly: Scand J Infect Dis). 2015, 47(11):808-819.

10. Qiu S, Pan H, Zhang S, Peng X, Zheng X, Xu G, Wang M,Wang J*, Lu H*. Is tuberculosis treatment really free in china? A study comparing two areas with different management models. PLoS One. 2015,10(5):e0126770.

11. Shao J, Shen Y, Lü J, Wang J*. Ultrasound scoring in combination with ultrasound elastography for differentiating benign and malignant thyroid nodules. Clin Endocrinol (Oxf). 201583(2)254-260

12. Feng Y, Wang F, Pan H, Qiu S, Lü J, Wu L, Wang J*, Lu C*. Obesity-associated gene FTO rs9939609 polymorphism in relation to the risk of tuberculosis. BMC Infect Dis. 2014,14(1):592

12. Sun X, Jiang K, Chen J, Wu L, Lu H, Wang A*, Wang J*.A systematic review of maggot debridement therapy for chronically infected wounds and ulcers. Int J Infect Dis. 2014, 25:32-7.

13. Huang S, Chen Y, Zhou J, Wang J*. Use of family member-based supervision in the management of patients with hypertension in rural China. Patient Prefer Adherence. 2014, 8:1035-42.

14. Lü J, Pan H, Chen Y, Tang S, Feng Y, Qiu S, Zhang S, Wu L, Xu R, Peng X, Wang J*, Lu C*. Genetic polymorphisms of IFNG and IFNGR1 in association with the risk of pulmonary tuberculosis.Gene. 2014, 543(1):140-4

15. Bele S, Jiang W, Lu H, You H, Fan H, Huang L, Wang Q, Shen H, Wang J*. Population aging and migrant workers: bottlenecks in tuberculosis control in rural china. PLoS One. 2014, 9(2):e88290.

16. Pan H, Bele S, Feng Y, Qiu S, Lv J, Tang S, Shen H, Wang J*, Zhu L*.Analysis of the economic burden of diagnosis and treatment of tuberculosis patients in rural China. Int J Tuberc Lung Dis . 2013,17(12) :1575-1580.

17. Wu LWang FXu RZhang SPeng XFeng Y, Wang J*, Lu C*. Promoter methylation of BRCA1 in the prognosis of breast cancer: a meta-analysis.Breast Cancer Res Treat. 2013, 142(3):619-27.

18. Xu R, Wang F, Wu L, Wang J*, Lu C*.A systematic review of hypermethylation of p16 gene in esophageal cancer. Cancer Biomarkers. 2013,13(4):215-226.

19. Wang F, Chen F, Huo X, Xu R, Wu L, Wang J*, Lu C*. A Neglected Issue on Sexual Well-Being following Breast Cancer Diagnosis and Treatment among Chinese Women. PLoS One. 2013, 8(9):e74473.

20. Wang JWu XKamat ABarton Grossman HDinney CPLin J. Fluid intake, genetic variants of UDP-glucuronosyltransferases, and bladder cancer risk. Br J Cancer. 2013,108(11):2372-80.

21. Feng Y, Liu S, Wang Q, Wang L, Tang S,Wang J*, Lu W*. Rapid Diagnosis of Drug Resistance to Fluoroquinolones, Amikacin, Capreomycin, Kanamycin and Ethambutol Using Genotype MTBDRsl Assay: A Meta-Analysis.PLoS One. 2013;8(2):e55292.

22. Dai Y, Feng Y, Xu R, Xu W, Lu W, Wang J*.Evaluation of interferon-gamma release assays for the diagnosis of tuberculosis: an updated meta-analysis. Eur J Clin Microbiol Infect Dis. 2012, 31(11):3127–3137. [Erratum in Eur J Clin Microbiol Infect Dis. 2013,32(7):967].

23. Pang H, Dai Y, Tang S, Wang J*. Polymorphisms of NOD2 and the risk of tuberculosis:a validation study in the Chinese population. Int J Immunogenet. 2012,39:233-240.

24. Dai Y, Zhang X, Pan H, Tang S, Shen H, Wang J*.Fine mapping of genetic polymorphisms of pulmonary tuberculosis within chromosome 18q11.2 in the Chinese population: a case-control study.BMC Infect Dis. 2011,11:282.

25. Shao Y, Yang D, Xu W, Lu W, Song H, Dai Y, Shen H, Wang J*. Epidemiology of Anti-tuberculosis Drug Resistance in a Chinese Population: Current Situation and Challenges Ahead. BMC Public Health 2011, 11:110.

26. Lu C, Xie H, Wang F, Shen H, Wang J*. Diet folate, DNA methylation and genetic polymorphisms of MTHFR C677T in association with the prognosis of esophageal squamous cell carcinoma. BMC Cancer. 2011;11:91.

27. Wang J*. Tang S. Shen H. Association of genetic polymorphisms in the IL12-IFNG pathway with susceptibility to and prognosis of pulmonary tuberculosis in a Chinese population. Eur J Clin Microbiol Infect Dis 2010, 29(10):1291-5.

28. Wang J, Lippman SM, Lee JJ, , Yang H, Khuri FR, Kim E, Lin J, Chang DW, Lotan R, Hong WK, Wu X. Genetic Variations in Regulator of G-Protein Signaling Genes as Susceptibility Loci for Second Primary Tumor/Recurrence in Head and Neck Squamous Cell Carcinoma. Carcinogenesis 2010, 31(10):1755- 61.

29. Xu W, Lu W, Zhou Y, Zhu L, Shen H,Wang J*. Adherence to anti-tuberculosis treatment among pulmonary tuberculosis patients: a qualitative and quantitative study. BMC Health Services Research. 2009,9:169.

30. Wang J, Shen H. Direct observation and completion of treatment of tuberculosis in rural areas of China. Scand J Public Health, 2009, 37(3):304-309.

31. Wang J, Shen H. Review of cigarette smoking and tuberculosis in China: intervention is needed for smoking cessation among tuberculosis patients. BMC Public Health. 2009,9:292.

32. Wang J, Fei Y, Shen H, Xu B. Gender difference in knowledge of tuberculosis and associated health-care seeking behaviors: a cross-sectional study in a rural area of China. BMC Public Health. 2008,8;8(1):354.

33. Wang JM, Sasco AJ, Fu CW, Xue HC, Guo GP, Jiang QW, Xu B. Aberrant DNA Methylation of P16, MGMT and hMLH1 Genes in Combination with MTHFR C677T Genetic Polymorphism in Esophageal Squamous Cell Carcinoma.Cancer Epidemiol Biomarkers Prev, 2008,17(1):118-125.

34. Wang JM, Xu B, Rao JY, Shen HB, Xue HC, Jiang QW. Diet Habits, Alcohol Drinking, Tobacco Smoking, Green Tea Drinking and the Risk of Esophageal Squamous Cell Carcinoma in the Chinese Population.Eur J Gastroenterol Hepatol 2007,19(2):171-176.

35. Wang JM, Xu B, Hsieh CC, Jiang QW. Longitudinal trends of stomach cancer and esophageal cancer in Yangzhong County: a high-incidence rural area of China. Eur J Gastroenterol Hepatol. 2005,17(12):1339-1344

 

5. Scholarly and Professional Activities

PI in “Molecular epidemiological study on the circRNA-based epigenetic regulatory network in esophageal cancer” funded by National Natural Science Foundation,550,000, 2017-2020

PI in “Molecular epidemiological study on the genetic and epigenetic traits of vitamin D metabolic pathway in the prognosis of tuberculosis” funded by National Natural Science Foundation,800,000, 2015-2018

PI in “Vitamin D and genetic variants of its metabolic pathway in association with sputum conversion time and prognosis in pulmonary tuberculosis patients” funded by National Natural Science Foundation,310,000, 2011-2013

PI in “Patterns of epigenetic changes of cancer suppressor genes in association with the early diagnosis and prognosis of esophageal cancer” funded by National Natural Science Foundation,580,000, 2012-2015

PI in “Research and application of biomarkers for the early detection and prognosis of female breast cancer”,510,000, 2015-2018

PI in “Treatment compliance and service availability of migrant tuberculosis patients in the South area of Jiangsu” funded by Philosophy and Social Science Research Projects in Colleges and Universities in Jiangsu,10,000, 2014-2016

PI in “Detection and control of drug resistant tuberculosis in Jiangsu Province” funded by Jiangsu Social Development Project Foundation,200,000, 2011-2014

PI in “Aberrant epigenetic profiles of circulated cell-free DNA for the early diagnosisand prognosis of breast cancer” funded by Key University Science Research Project of Jiangsu Province,150,000, 2012-2015

PI in “Development of a family member-based education package for patients with hypertension in rural China” funded by Chinese Medical Board, $40,000, 2011-2014

PI in “The relation between genetic polymorphisms and anti-tuberculosis drug resistance under dots strategy” funded by Natural Science Foundation of Jiangsu,70,000, 2009-2010

PI in “Genetic polymorphisms of IFN-γin the prognosis of TB” sponsored by China Postdoctoral Science Foundation,30,000, 2008-2009