张雪梅

Zhang Xuemei

  

1. Personal Information

Title/Position: Associate Professor

Correspondence Address:Department of Toxicology, Nanjing Medical University, 101 Longmian Av., Jiangning District, Nanjing, Jiangsu Province, 211166, P.R. China.

Telephone: 86-25-86868425

Fax: 86-25-8686-8499

E-mail: xuemeizhang@njmu.edu.cn

  

2. Education

INSTITUTION

DEGREE

(if applicable)

MM/YY

FIELD OF STUDY

China Medical University

  B.S.

  07/01

Prevention Medicine

Fudanl University

  M.S.

  07/04

Molecular Toxicology

Temple University

Ph.D.

10/09

Anatomy and Cell Biology

 

3. Research Interests

My lab is primarily focused on Nanotoxicity and the protential molecular & cellular mechanisms.

 

4. Selected Publications

1)Zhang X, Song Y, Shah AY, Lekova V, Raj A, Huang L, Behlke MA, Tsourkas A. Quantitative Assessment of Ratiometric BiMolecular Beacons as a Tool for Imaging Single Engineered RNA Transcripts and Measuring Gene Expression in Living Cells. Nucleic Acids Res. 2013, Aug 1; 41(15):e152.

2)Song Y*, Zhang X*, Huang L, Behlke MA, Tsourkas A. Real-time Imaging of Single Engineered RNA Transcripts in Living Cells Using Ratiometric Bimolecular Beacons. J Vis Exp. 2014 Aug 6;(90):e51544.*co-first author

3)Zhang X, Zajac, A, Huang L, Behlke MA, Tsourkas A. Imaging the Directed Transport of Single Engineered RNA Transcripts in Real-time Using Ratiometric Bimolecular Beacons. PLoS ONE , 2014 Jan 15;9(1):e85813

4)Zhang X*, Arnott JA*, Rehman S, Delong WG Jr, Sanjay A, Safadi FF, Popoff SN. Src is a Major Signaling Component for CTGF Induction by TGF-beta1 in Osteoblasts. J Cell Physiol. 2010; 224(3):691-701. *co-first author

5)Arnott JA*, Zhang X*, Sanjay A, Owen TA, Smock SL, Rehman S, DeLong WG, Safadi FF, Popoff SN. Molecular Requirements for Induction of CTGF Expression by TGF-beta1 in Primary Osteoblasts. Bone. 2008; 42(5): 871- 85 . *co-first author

6)Xu B, Chen M, Ji X, Mao Z, Zhang X, Wang X, Xia Y. Metabolomic Profiles Delineate the Potential Role of Glycine in Gold Nanorod-induced Disruption of Mitochondria and Blood-testis Barrier Factors in TM-4 Cells. Nanoscale. 2014 Jul 21;6(14):8265-73.

7)Mao Z, Xu B, Ji X, Zhou K, Zhang X, Chen M, Han X, Tang Q, Wang X, Xia Y. Titanium Dioxide Nanoparticles Alter Cellular Morphology via Disturbing the Microtubule Dynamics. Nanoscale. 2015, 7(18):8466-75

8)Giraldo-Vela JP, Kang W, McNaughton RL, Zhang X, Wile BM, Tsourkas A, Bao G, Espinosa HD. Single-cell Detection of mRNA Expression Using Nanofountain-probe Electroporated Molecular Beacons. Small. 2015, 11(20):2386-91.

9)Wei X, Jia Y, Xue Y, Geng L, Wang M, Li L, Wang M, Zhang X, Wu X. GDNF-expressing STO feeder layer supports the long-term propagation of undifferentiated mouse spermatogonia with stem cell properties. Sci Rep. 2016 Nov 9;6: 36779.

  

5. Scholarly and Professional Activities

Member, Chinese Society of Toxicology (CST)

Member, America Society of Toxicology