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王军 |
Wang Jun 1. Personal Information Title/Position: Associated professor Correspondence Address:Department of Toxicology, School of Public Health, Nanjing Medical University,101 Longmian Av., Jiangning District, Nanjing, Jiangsu Province, 211166, P.R. China. Telephone: 86-25-86868431 Fax: 86-25-8686-8499 E-mail:wangjun@njmu.edu.cn
2. Education
3. Research Fields (1) neurotoxity of drug abusing (2) neurotoxity of endocrine disrupt chemicals
4. Selected Publications 1.Fang F, Gao Y, Wang T, Chen D, Liu J, Qian W, Cheng J, Gao R,Wang J(Co-Correspondence author)Xiao H.Insulin signaling disruption in male mice due to perinatal bisphenol A exposure: Role of insulin signaling in the brain. Toxicol Lett. 2016,245:59-67. 2.Xufeng Chen , Jingjing Xing, Lei Jiang ,Wenyi Qian, Yixin Wang, Hao Sun, Yu Wang, Hang Xiao, Jun Wang(Co- Correspondence author), Jinsong Zhang. Involvement of Calcium/calmodulin-dependent Protein Kinase II in Methamphetamine Induced Neural Damage. J Appl Toxicol. 2016,36(11):1460-7. 3.Li J, Wang Y, Fang F, Chen D, Gao Y, Liu J, Gao R,Wang J(Co- Correspondence author), Xiao H. Bisphenol A disrupts glucose transport and neurophysiological role of IR/IRS/AKT/GSK3β axis in the brain of male mice.Environ Toxicol Pharmacol. 2016, 43:7-12. 4.Chen J,Wang J(Co-first author), Su C, Qian W, Sun L, Sun H, Chen J, Zhang H, Zhang J.Urinary trypsin inhibitor attenuates LPS-induced endothelial barrier dysfunction by upregulation of vascular endothelial-cadherin expression. Inflamm Res. 2016. 65(3):213-24. 5.Zhu Q, Song X, Zhou J, Wang Y, Xia J, Qian W, Zhu J, Gao R,Wang J(Co- Correspondence author), Xiao H.Target of HIV-1 Envelope Glycoprotein gp120-Induced Hippocampal Neuron Damage: Role of Voltage-Gated K(+) Channel Kv2.1. Viral Immunol. 2015,28(9):495-503. 6. Qian W, Wang Y, Zhu J, Mao C, Wang Q, Huan F, Cheng J, Liu Y,Wang J(Correspondence author), Xiao H.The toxic effects of Bisphenol A on the mouse spermatocyte GC-2 cell line: the role of the Ca2+ -calmodulin-Ca2+ /calmodulin-dependent protein kinase II axis. J Appl Toxicol. 2015, 5(11):1271-7 7. Zhu J, Qian W, Wang Y, Gao R,Wang J(Correspondence author), Xiao H.Involvement of mitogen-activated protein kinase and NF-κB signaling pathways in perfluorooctane sulfonic acid-induced inflammatory reaction in BV2 microglial cells. J Appl Toxicol. 2015, 35(12):1539-49. 8. Fang F, Chen D, Yu P, Qian W, Zhou J, Liu J, Gao R,Wang J(Co- Correspondence author), Xiao H.Effects of Bisphenol A on glucose homeostasis and brain insulin signaling pathways in male mice. Gen Comp Endocrinol. 2015,212:44-50. doi: 10.1016/j.ygcen. 9.Lei Jiang, Yixin Wang, Chenglei Su, Hao Sun, Huazhong Zhang, Baoli Zhu, Hengdong Zhang, Hang Xiao,Jun Wang(Co- Correspondence author), Jinsong Zhang. Epithelial sodium channel is involved in H2S-induced acute pulmonary edema. Inhalation Toxicology,2015,27 12): 613-20. 10. Zhu J, Jiang L, Liu Y, Qian W, Liu J, Zhou J, Gao R, Xiao H,Wang J(Correspondence author).MAPK and NF-κB pathways are involved in bisphenol A-induced TNF-α and IL-6 production in BV2 microglial cells. Inflammation. 2015, 38(2):637-48. 11. Jiang L, Wang J(Co-first author), Su C, Qian W, Chen J, Zhu B, Zhang H, Xiao H, Zhang J.α-ENaC, a therapeutic target of dexamethasone on hydrogen sulfide induced acute pulmonary edema. Environ Toxicol Pharmacol. 2014,38(2): 616-24. 12.Qian W, Zhu J, Mao C, Liu J, Wang Y, Wang Q, Liu Y, Gao R, Xiao H,Wang J(Correspondence author).Involvement of CaM-CaMKII-ERK in bisphenol A-induced Sertoli cell apoptosis. Toxicology. 2014,324: 27-34. 13.Wang J, Zhang H, Su C, Chen J, Zhu B, Zhang H, Xiao H, Zhang J.Dexamethasone ameliorates H2S-induced acute lung injury by alleviating matrix metalloproteinase-2 and -9 expression. PLoS One. 2014,9(4):e94701. 14.Wang J, Qian W, Liu J, Zhao J, Yu P, Jiang L, Zhou J, Gao R, Xiao H. Effect of methamphetamine on the microglial damage: role of potassium channel Kv1.3. PLoS One. 2014,9(2):e88642. 15. Zhang X, Wang J(Co-first author),Qian W, Zhao J, Sun L, Qian Y, Xiao H.Dexmedetomidine inhibits tumor necrosis factor-alpha and interleukin 6 in lipopolysaccharide-stimulated astrocytes by suppression of c-Jun N-terminal kinases. Inflammation. 2014,37(3):942-9. 16.Wang J, Qian W, Zhu Q, Chen J, Huan F, Gao R, Xiao H.Martentoxin, a large-conductance Ca(2+)-activated K(+) channel inhibitor, attenuated TNF-α-induced nitric oxide release by human umbilical vein endothelial cells. J Biomed Res. 2013,27(5):386-93. 17. Liu J, Yu P, Qian W, Li Y, Zhao J, Huan F,Wang J(Co-Correspondence author), Xiao H.Perinatal bisphenol A exposure and adult glucose homeostasis: identifying critical windows of exposure.PLoS One. 2013, 8(5):e64143.
5. Scholarly and Professional Activities Member, Chinese Society of Toxicology (CST) Member, Chinese Academy of Neuroscience Committee member of Emergency and critical care quality management
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