Name: HAN FENG
Position : Professor, Dean
E-mail :Fenghan69@njmu.edu.cn
Affiliation: Key Laboratory of Cardiovascular and Cerebrovascular Medicine, School of Pharmacy, Nanjing Medical University
Research Interests:
1. Molecular mechanisms of cerebrovascular diseases and potential drug Targets for pharmaceutical intervention.
2. Cerebrovascular biology and pathophysiological regulation of the cerebral microcirculation in brain diseases.
Grants:
The State Key Program of National Natural Science of China (grant 81730101);
The National Key Research and Development Program of China (2016YFE0125400);
The National Natural Science Foundations of China (81573411).
Selected Publications:
More than 5 0 research articles or reviews published .
1. Tan C, Lu NN, Wang CK, Chen DY, Sun NH, et al, Lu YM*, Han Feng . Endothelium-Derived Semaphorin 3G Regulates Hippocampal Synaptic Structure and Plasticity via Neuropilin-2/PlexinA4. Neuron . 2018, In Proof
2. Lu NN, Tan C, Sun NH, Shao LX, Liu XX, Gao YP, Tao RR, Jiang Q, Wang CK, Huang JY, Zhao K, Wang GF, Liu ZR, Fukunaga KJ, Lu YM*, Han Feng Cholinergic Grb2-associated-binding protein 1 regulates cognitive function. Cerebral Cortex . 2017: 28(7): 2391-2404
3. Wang CK, Ahmed MM, Jiang Q, Lu NN, Tan C, Gao YP, Mahmood Q, Chen DY, Fukunaga K, Li M, Chen Z, Wilcox CS, Lu YM, Qin ZH*, Han Feng . Melatonin Ameliorates Hypoglycemic stress-induced brain endothelial tight junction injury by inhibiting protein nitration of TP53-induced glycolysis and apoptosis regulator. J Pineal Research. 2017 Nov;63(4). doi: 10.1111/jpi.12440
4. Jiang Q, Gao Y, Wang C, Tao R, Wu Y, Zhan K, Liao M, Lu N, Lu Y, Wilcox CS, Luo J, Jiang LH*, Yang W*, Han Feng . Nitration of TRPM2 As a Molecular Switch Induces Autophagy During Brain Pericyte Injury. Antioxid Redox Signal 2017. 27(16): 1297-1316
5. Wang H, Hong LJ, Huang JY, Jiang Q, Tao RR, Tan C, Lu NN, Wang CK, Ahmed MM, Lu YM, Liu ZR, Shi WX, Lai EY, Wilcox CS, Han Feng . P2RX ( 7 Sensitizes Mac-1/ICAM-1-dependent leukocyte-endothelial adhesion and promotes neurovascular injury during septic encephalopathy. Cell Research. 2015 Jun;25(6):674-90.
6. Li X, Tao RR, Hong LJ, Cheng J, Jiang Q, Lu YM, Liao MH, Ye WF, Lu NN, Han Feng , Hu YZ, Hu YH. Visualizing Peroxynitrite Fluxes in Endothelial Cells Reveals the Dynamic Progression of Brain Vascular Injury. J American Chemical Society 2015.
Pro fessor Feng Han is the Dean of Nanjing medical university pharmaceutical college. His main focus was on the research of the pathogenesis, molecular markers and drug discovery around the cardiovascular and cerebrovascular diseases. He is the Associate Editor of Journal of Pharmacological Sciences, Editorial Board Of Journal of Pineal Reearch,Visiting Professor of Tohoku University and Standing Committee Member of Cardiovascular and Cerebrovascular Pharmacology Committee of Chinese Pharmacology Society. Recently, he has hosted key projects of the National Natural Science Foundation, Key International Cooperation Research Projects, and major research projects. He was awarded the first prize of the University Research Achievement Award by the Ministry of Education , The Provincial Natural Science Award and so on. He has published more than 60 SCI papers, including Cell Research, Of The American Chemical Society, and Journal of Pineal Research.
