张展

Zhang Zhan

1. Personal Information

Title/Position: Lecturer

Correspondence Address:Department of Hygiene Analysis and Detection, Nanjing Medical University, 101 Longmian Av., Jiangning District, Nanjing, Jiangsu Province, 211166, P.R. China.

Telephone: 86-25-86868402

Fax: 86-25-86868499

E-mail: zhanzhang@njmu.edu.cn

  

2. Education

INSTITUTION

DEGREE

MM/YY

FIELD OF STUDY

Nanjing Medical University

B.S.

07/09

Prevention Medicine

Nanjing Medical University

Ph.D.

07/14

Metabolic Toxicology

 

3. Research Interests

1. microorganism inspection,

2. role of microorganism in chronic diseases.

 

4. Selected Publications

1. Zhan Zhang, XinYue Wu, Shuyuan Cao, Li Wang, Di Wang, Hui Yang,Yiming Feng, Shoulin Wang, Lei Li. Caffeic acid ameliorates colitis in association with increased Akkermansia population in the gut microbiota of mice.Oncotarget, 2016, 7(22): 31790-9.

2. Zhan Zhang, Shushu Li, Lu Liu, Li Wang, Xue Xiao, Zhenzhen Sun, Xichen Wang, Chao Wang, Meilin Wang, Lei Li, Qiujin Xu, Weimin Gao, Shou-Lin Wang. Environmental exposure to BDE47 is associated with increased diabetes prevalence: Evidence from community-based case-control studies and an animal experiment.Scientific Reports, 2016, 6:27854.

3. Yun Wang, Zhan Zhang*, Huanqiang Wang, Yudong Zhang, Minghui Ji, Hengsen Xu, Chao Wang, Zhenzhen Sun, Weimin Gao, Shou‑Lin Wang. miR-138-1*regulates aflatoxin B1-induced malignant transformation of BEAS-2B cells by targeting PDK1. Archives of Toxicology, 2016. 90(5): 1239-49. ( *Authors contributed equally)

4. Zhenzhen Sun, Zhan Zhang*, Minghui Ji, Hongbao Yang, Meghan Cromie, Jun Gu, Chao Wang, Lu Yang, Yongquan Yu, Weimin Gao, Shou-Lin Wang.BDE47 induces rat CYP3A1 by targeting the transcriptional regulation of miR-23b.Scientific Reports, 2016, 6,31958. ( *Authors contributed equally)

5. Shuyuan Cao*, Zhan Zhang* , Yuting Ye, Lijun Chen, Yuan Li, Xinyu Yu, Ye Yang, Li Wang, Zhong Li, Lei Li.Metabolic transformation evidence of caffeic acid derivatives in male rat after oral administration of functional food by UPLC coupled with hybrid quadrupole-orbitrap mass spectrometer. RSC Advances, 2015, 5(22): 16960-16967. ( *Authors contributed equally)

6. Jun Zhao*, Zhan Zhang*, Jinfeng Dai, Li wang, Chengxiang Zhang, Yuting Ye, Lei Li. Synergistic protective effect of chlorogenic acid, apigenin and caffeic acid against carbon tetrachloride-induced hepatotoxicity in male mice. RSC Advances, 2014, 4(81): 43057-43063. ( *Authors contributed equally)

7. Zhan Zhang,Huiyuan Lu, Fei Huan, Cromie Meghan, Xuejiao Yang, Yun Wang, Xichen Wang, Xinru Wang, Shoulin Wang. Cytochrome P450 2A13 mediates the neoplastic transformation of human bronchial epithelial cells at a low concentration of aflatoxin B1. International Journal of Cancer, 2014, 134(7): 1539-1548.

8. Zhan Zhang, Xuejiao Yang, Yun Wang, Xichen Wang, Huiyuan Lu, Xiaoming Zhang, Xue Xiao, Shushu Li, Xinru Wang, Shoulin Wang. Cytochrome P450 2A13 is an efficient enzyme in metabolic activation of aflatoxin G1 in human bronchial epithelial cells. Archives of Toxicology, 2013, 87(9): 1697-1707.

9. Zhan Zhang, Zhenzhen Sun, Xue Xiao, Shixin Zhou, Xichen Wang, Jun Gu, Liang‑Lin Qiu, Xuhui Zhang, Qiujin Xu, Binghui Zhen, Xinru Wang, Shoulin Wang. Mechanism of BDE209-induced impaired glucose homeostasis based on gene microarray analysis of adult rat liver. Archives of Toxicology, 2013, 87(8): 1557-1567.

10. Zhan Zhang, Xiaoming Zhang, Zhenzhen Sun, Huibin Dong, Lianglin Qiu, Jun Gu, Jingping Zhou, Xinru Wang, Shoulin Wang. Cytochrome P450 3A1 mediates 2,2',4,4'-tetrabromodiphenyl ether-Induced reduction of spermatogenesis in adult rats. PLoS One, 2013, 8(6): e66301.

11. Xuejiao Yang*,Zhan Zhang*, Xichen Wang, Yun Wang, Xiaoming Zhang, Huiyuan Lu, Shoulin Wang. Cytochrome P450 2A13 enhances the sensitivity of human bronchial epithelial cells to aflatoxin B1-induced DNA damage. Toxicology and Applied Pharmacology, 2013, 270(2): 114-121. ( *Authors contributed equally)

 

5. Scholarly and Professional Activities

Member, Chinese Society of Toxicology (CST)