陈进

Chen Jin

  

1. Personal Information

Title/Position: Professor

Correspondence Address: School of Public Health, Nanjing Medical University, 101 Longmian Av., Jiangning District, Nanjing, Jiangsu Province, 211166, P.R. China.

Telephone: 86-25-86868248

E-mail: jchen@njmu.edu.cn

  

2. Education

INSTITUTION

DEGREE

MM/YY

FIELD OF STUDY

Nanjing University

B.S.

06/01

Chemistry

Nanjing University

Ph.D.

09/06

Bioanalytical Chemistry

 

3. Research Interests

Our lab has been mainly focused on the following topics:

1. Developing biosensing platforms including cytosensors for the sensitive determination of tumor markers and for the evaluation of cytotoxicity.

2. Protein-based functional materials used for modern bioanalysis.

 

4. Selected Publications

Peer-reviewed articles as corresponding author:

1. Xu, Z. et al. A general method to regenerate arrayed gold microelectrodes for label-free cell assay. Anal. Biochem. 516, 57-60 (2017).

2. Wang, H. Q. et al. Three-Dimensionally controllable synthesis of multichannel silica nanotubes and their application as dual drug carriers. ChemPlusChem 80, 1615-1623 (2015).

3. Chen, J. et al. Self-assembly of the chaperonin GroEL nanocage induced at submicellar detergent. Sci. Rep. 4 (2014).

4. Zhang, Q.#, Chen, J.# Nucleotide-induced conformational changes of tetradecameric GroEL mapped by H/D exchange monitored by FT-ICR mass spectrometry. Sci. Rep. 3, 1247 (2013). #co-first

5. Chen, J. et al. Fibrillogenic propensity of the GroEL apical domain: A Janus-faced minichaperone. Febs Lett. 586, 1120-1127 (2012).

 

5. Scholarly and Professional Activities

Oral talk

Nucleotide-induced GroEL conformational changes, The 3rd Korea-Japan seminar on biomolecular sciences, Jeju, Korea, 2011

Alpha-crystallin domain assembly and GroEL dynamics, Workshop on recent advances in protein folding and molecular chaperones, Beijing, China, 2010.

Dissect a bimolecular mechanism of ATP binding to the chaperonin GroEL, OzBio2010 conference, Melbourne, Australia, 2010.

 

Honors

Specially-appointed professor of Jiangsu Province, 2015

Young eastern scholar, Shanghai, 2015

Young Investigator Travel Grant, The Protein Society, USA, 2012

International YSF fellowship, IUBMB, Australia, 2010

Alexander von Humboldt Fellowship, Germany, 2006-2008