王守林

Wang ShouLin

 

1. Personal Information

Title/Position: Professor

Correspondence Address: Correspondence Address:Department of Occupational Medicine and Environmental Health, Nanjing Medical University, 101 Longmian Av., Jiangning District, Nanjing, Jiangsu Province, 211166, P.R. China.

Telephone: 025-8686 8417 (Office) / 025-8686 8429 (Lab)

E-mail: wangshl@njmu.edu.cn

  

2. Education

INSTITUTION

DEGREE

MM/YY

FIELD OF STUDY

Nanjing Medical University

B.S.

07/1991

Preventive Medicine

Nanjing Medical University

M.S.

07/1999

Occupational & Environmental Health

Nanjing Medical University

Ph.D.

07/2006

Occupational & Environmental Health

National University of Singapore

Visiting Scholar

10/99-04/00

Reproductive Epidemiology

University of Medicine & Dentistry of New Jersey, New Jersey, USA

Visiting Scholar

04/03-03/06

Cellular & Molecular Toxicology

 

3. Research Interests

    I am currently conducting research in three areas: (1) Biotransformation and the function of metabolic enzymes; (2) Reproductive and development toxicology; (3) Environment-gene interaction and health risk assessment.

 

4. Selected Publications (* Corresponding Author)

1.Sun ZZ, Zhang Z, Ji M, Yang H, Cromie M, Gu J, Wang C, Yang L, Yu Y, Gao W, and Wang SL*. BDE47 induces rat CYP3A1 by targeting the transcriptional regulation of miR-23b. Sci Rep. 2016; 6:31958.

2.Wang C, Yang L, Wang S, Zhang Z, Yu Y, Wang M, Cromie M, Gao W, and Wang SL*. The classic EDCs, phthalate esters and organochlorines, in relation to abnormal sperm quality: a systematic review with meta-analysis. Sci Rep 2016, 6:19982

3.Wang Y, Zhang Z, Wang H, Zhang Y, Ji M, Xu H, Wang C, Sun Z, Gao W, and Wang SL*. miR-138-1* regulates aflatoxin B1-induced malignant transformation of BEAS-2B cells by targeting PDK1. Arch Toxicol 2016; 90(5):1239-1249,

4.Zhang Z, Li S, Liu L, Wang L, Xiao X, Sun Z, Wang X, Wang C, Wang M, Li L, Xu Q, Gao W, and Wang SL*. Environmental exposure to BDE47 is associated with increased diabetes prevalence: Evidence from community-based case-control studies and an animal experiment. Sci Rep 2016;6:27854.

5.Xiao X, Ma G, Li S, Wang M, Liu N, Ma L, Zhang Z, Chu H, Zhang Z, and Wang SL*. Functional POR A503V is associated with the risk of bladder cancer in a Chinese population. Sci Rep 2015, 5:11751.

6.Zhang Z, Lu H, Huan F, Meghan C, Yang X, Wang Y, Wang X, Wang X, Wang SL*. Cytochrome P450 2A13 mediates the neoplastic transformation of human bronchial epithelial cells at a low concentration of aflatoxin B1. Int J Cancer. 2014 Apr 1;134(7):1539-1548.

7.Zhang Z, Yang X, Wang XC, Wang Y, Lu H, Zhang X, Xiao X, Li S, Wang X, Zhang Z, and Wang SL*. Cytochrome P450 2A13 is an efficient enzyme in metabolic activation to aflatoxin G1 in human bronchial epithelial cells. Arch Toxicol, 2013 Sept, 87(9):1697-1707.

8.Yang X, Zhang Z, Wang X, Wang Y, Zhang X, Lu H, Wang SL*. Cytochrome P450 2A13 enhances the sensitivity of human bronchial epithelial cells to aflatoxin B1-induced DNA damage. Toxicol Appl Pharmacol. July 15,2013;270(2):114-121

9.Qiu L, Zhang X, Zhang X, Zhang Y, Gu J, Chen M, Zhang Z, Wang X, Wang SL*. Sertoli cell is a potential target for perfluroocatane sulfonate (PFOS)-induced reproductive dysfunction in male mice. Toxicol Sci. 2013 Sep;135(1):229-240.

10.Zhang Z, Sun ZZ, Xiao X, Zhou S, Wang XC, Gu J, Qiu LL, Zhang XH, Xu QJ, Zhen B, Wang X, Wang SL*. Mechanism of BDE209-induced impaired glucose homeostasis based on gene microarray analysis of adult rat liver. Arch Toxicol. 2013 Aug;87(8):1557-67.

 

5. Scholarly and Professional Activities

(1)Member, Chinese Society of Toxicology

(2)Vice chairman, Jiangsu Society of Toxicology

(3)Executive expert, Department of cosmetics, State Food and Drug Administration

(4)Member, Department of Environmental Health, Association of Preventive Medicine of Jiangsu Province