顾爱华

Gu Aihua

  

1. Personal Information

Title/Position: Ph.D., Professor

Correspondence Address: 101 Longmian Av., Jiangning District, Nanjing, Jiangsu Province, 211166, P.R. China.

Telephone: (86)-25-86868407

E-mail: aihuagu@njmu.edu.cn

  

2. Education

INSTITUTION

DEGREE

(if applicable)

MM/YY

FIELD OF STUDY

Nanjing Medical University

            B.S.

            07/01

Clinical Medicine

Nanjing Medical University

            M.S.

            07/04

Medicine

Nanjing Medical University

Ph.D.

05/07

Toxicology

 

3. Title / position

2015- : Professor (tenure), Nanjing Medical University, School of Public Health.

2015- : Director of Scientific Research Center, Nanjing Medical University.

2013-2014: Program Director, National Natural Science Foundation of China, Department of Health Science, Beijing, China.

2010-2013: Associate Professor (tenure), Nanjing Medical University, School of Public Health.

2008-2010: Assistant Professor (tenure-track), Nanjing Medical University, School of Public Health.

4. Teaching appointments

Hygiene (course director)

Toxicology (course director)

Environmental Health Perspectives (guest lecturer)

 

5. Research Interests

²Reproductive and Developmental Toxicology: a) The hazard of environmental-genetic dangerous factors and their interactions to reproduction and development; b) The study of developmental toxicology and environmental toxicology using zebrafish model system; c) The key roles of DNA damage repair events in important time windows during gametogenesis and embryogenesis;

²Grants

1)National Science Foundation of China (Grant No.81573174), 840,000 RMB, 2016-2019, PI

2)National Science Foundation of China (Grant No.81172694), 620,000 RMB, 2012-2015, PI

3)National Science Foundation of China (Grant No.30901210), 190,000 RMB, 2009-2011, PI

4)Outstanding Youth Fund of Jiangsu Province (SBK2014010296), 1000,000 RMB, 2014-2017, PI

5)Research Project of Chinese Ministry of Education (213015A), 500,000 RMB, 2013-2016, PI

 

²Selected Publications

1)Fan HB, Liu YJ, Wang L, Du TT, Dong M, Gao L, Meng ZZ, Jin Y, Chen Y, Deng M, Yang HT, Jing Q,Gu AH*, Liu TX, Zhou Y*.miR-142-3p acts as an essential modulator of neutrophil development in zebrafish.Blood. 2014 Aug 21;124(8):1320-30.

2)Dong ZW, Ren CG, Xia Y, Su D, Du TT, Fan HB, Yuan H, Wang L, Dong M, Li WC, Jin Y, Chen Y, Deng M, Liu TX, Gu AH*, Zhou Y*.Pten regulates homeostasis and inflammation-induced migration of myelocytes in zebrafish. J Hematol Oncol.2014 Mar 5;7:17.

3)Wang L, Fu C, Fan H, Du T, Dong M, Chen Y, Jin Y, Zhou Y, Deng M, Gu A*, Jing Q*, Liu T, Zhou Y*.miR-34b regulates multiciliogenesis during organ formation in zebrafish. Development2013 Jul;140(13):2755-64.

4)Ji G, Yan L, Liu W, Qu J, Gu A. OGG1 Ser326Cys polymorphism interacts with cigarette smoking to increase oxidative DNA damage in human sperm and the risk of male infertility. Toxicol Lett. 2013,218(2):144-9.

5)Chen P, Zou P, Yan Q, Xu H, Zhao P,Gu A. The TERT MNS16A polymorphism contributes to cancer susceptibility: Meta-analysis of the current studies. Gene. 2013 Feb 24.

6)Long Y, Wang Y, Ji G, Yan L, Hu F, Gu A. Neurotoxicity of Perfluorooctane Sulfonate to Hippocampal Cells in Adult Mice. PLoS One. 2013;8(1):e54176.

7)Ji G, Long Y, Zhou Y, Huang C, Gu A, Wang X. Common variants in mismatch repair genes associated with increased risk of sperm DNA damage and male infertility. BMC Med. 2012,10:49.  

8)Gu A, Ji G, Jiang T, Lu A, You Y, Liu N, Luo C, Yan W, Zhao P. Contributions of Aryl Hydrocarbon Receptor (AHR) Genetic Variants to the Risk of Glioma and PAH-DNA adducts. Toxicol Sci. 2012,128(2):357-64. 

9)Ji G, Gu A, Wang Y, Huang C, Hu F, Zhou Y, Song L, Wang X. Genetic variants in antioxidant genes are associated with sperm DNA damage and risk of male infertility in a Chinese population. Free Radic Biol Med. 2012,52(4):775-80. 

10)Yan L, Zhao L, Long Y, Zou P, Ji G, Gu A, Zhao P. Association of the maternal MTHFR C677T polymorphism with susceptibility to neural tube defects in offsprings: evidence from 25 case-control studies. PLoS One. 2012;7(10):e41689.

11)Gu A, Ji G, Long Y, Zhou Y, Shi X, Song L, Wang X. Assessment of an association between an aryl hydrocarbon receptor gene (AHR) polymorphism and risk of male infertility. Toxicol Sci. 2011, 122(2):415-21.  

12)Gu A, Shi X, Yuan C, Ji G, Zhou Y, Long Y, Song L, Wang S, Wang X. Exposure to fenvalerate causes brain impairment during zebrafish development. Toxicol Lett. 2010,197(3):188-92.